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EUROPEAN MEDICINES AGENCY

SCIENCE MEDICINES HEALTH

25 January 2011

EMA/HMPC/576233/2010

Committee on Herbal Medicinal Products (HMPC)

List of references supporting the assessment of Fumaria officinalis L., herba

Draft

The Agency acknowledges that copies of the underlying works used to produce this monograph were provided for research only with exclusion of any commercial purpose.

Anderson L, Phillipson JD. Herbal medicine, education and the pharmacist. Phar J 1986, 236: 303. Abstract only.

Barnes J, Anderson LA, Phillipson JD. Herbal Medicines. 2^nd ed. Pharmaceutical Press, London 2002.

Blumenthal M, Busse WR, Goldberg A, Gruenwald J, et al., editors. The Complete German Commission E Monographs. American Botanical Council, Austin Texas 1998, 221.

Boegge SC, Narhstedt A, Linscheid M, Nigge W. Distribution and Stereochemistry of Hydroxy-cinnamoylmalic Acids and Free malic acids in Papaveraceae and Fumariaceae. Z Naturforsch 1995,

50c: 608-615.

Bonnet D, Mejdoubi S, Sommet A, Alric L. Hépatite aiguë probablement imputable au fumeterre et à la vigne rouge, produits de phytothérapie. Gastroentérol Clin Biol 2007, 31(11): 1041-1042. Abstract only.

Boucard M, Laubenheimer B. Action du nébulisat de fumeterre sur le débit bilaire du rat. Therapie 1966, 21: 903-911.

Bourjat P. Xérostomies par radiothérapie. Essais de traitement par le nébulisat de Fumaria officinalis. [Xerostomia due to radiotherapy: trials of treatment with nebulizate of Fumaria officinalis.] Gazette Med Fr 1974, 81(12): 1549-1552. Abstract only.

Brinkhaus B, et al. Herbal medicine with curcuma and fumitory in the treatment of irritable bowel syndrome: a randomized, placebo- controlled, double-blind clinical trial. Scand J Gastroenterol 2005, 40: 936-43. Abstract only.

British Herbal Pharmacopoeia (BHP). Vol. 1. Fumitory. Fumariae herba. British Herbal Medicine Association, Exeter 1976, 91.

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© European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

British Herbal Compendium. Part 1. Bradley PR editor. Fumitory. Fumariae herba. British Herbal Medicine Association, Bournemouth 1992, 102-104.

Bulletins Officiels N° 86/20 bis and N° 90/22 bis, Direction de la Pharmacie et du Médicament, French Health Authorities, 1986.

Cahier de l'Agence n° 3 : Médicaments à base de plantes. Fumeterre Ed. Agence du Médicament, Paris 2008.

Delaveau. Fumeterre. Les actualites pharmaceutiques 1980, 172: 33-34.

Denden S, Braham W, Gorcii Aloui S, Lakhdar R, Kahloun H, Mahdouani K, Knani J, Haj Khelil A. Analyse biologique et phytotherapie Clinique de l'asthme dans une population de la Tunisie centrale. Acta Horticulture 2010, 853: 391-396.

Dil AH. Activité anti-histaminique de la fumarine. Therapie 1973, 28: 767-774. Abstract only.

Duke JA. Handbook of Medicinal Herbs. 2^nd ed. CRC Press, Boca Raton 2002.

ESCOP Monographs. 2^nd ed. Cynarae folium. European Scientific Cooperative on Phytotherapy, editor. Georg Thieme Verlag, Stuttgart 2003.

European Pharmacopoeia 6.2. 1/2008: 1952.

Fablet J, Coluin R, Geffroy Y. Action thérapeutiques du Fumaria officinalis dans le syndrome hepatobiliaires et les migraines. Actualité Therap 1968, 3376-3379.

Fiegel G. Die amphocholoretische Wirkung der Fumaria officinalis. Z Allgemeinmed Landarzt 1971, 34: 1819-1820.

Forgacs P, et al. Alcaloides des Papavéracées II: Composition chimique de dix-sept espèces de Fumaria. Plantes Med Phytother 1986, 20: 64-81. Abstract only.

Forgacs P, et al. Composition chimique des Fumariacées. Alcaloides de quatorze espèces de Fumaria. Plantes Med Phytother 1982, 16: 99-11. Abstract only.

Goetz P, Ghedira K, Le Jeune R. Fumaria officinalis L. (Fumariaceae). Phytotherapie 2009, 7: 221-225.

Goldberg A, Brinckmann J, eds. Herbal medicine: Expanded Commission E monographs. American Botanical Council, Austin, Texas 2000.

Gorbunov NP, Molokhova LG, Shukhanov AA. Preparation and the arrhythmic activity of the total alkaloids of Fumaria officinalis L. Pharm Chem J 1977, 11(5): 640-642.

HagerROM. Handbuch der Drogen und Arzneistoffe, update. Blaschek W, Ebel S, Hackethal E,

Holzgrabe U, Keller K, Reichling J, editors. Fumaria herba. Springer Verlag, Berlin, Heidelberg 2006.

Hahn R, Nahrstedt A. High content of Hydroxycinnamic Acids esterified with (+) D-malic Acid in the upper parts of Fumaria officinalis. Planta Medica 1985, 59(2): 189.

Heully F, Drouin P, Laurant J, Bas M, Mauuary G. Appreciation Des propriétés cholérétiques du nebulisat de Fumaria officinalis par le tubage duodenal minute. Ann Med Nancy 1969, 8: 295-299.

Hermansson J, Sandberg F. Alkaloids of Fumaria officinalis. Acta Pharm Suec 1973, 10: 520-522. Abstract only.

Hunold W. Klinische erfahrungen mit dem amphocholeretikum oddibil bei primar und sekundar organischen sowie funktionellen cholezysto- und cholangiohepatopathien. [Clinical experience with Fumaria officinalis ('Oddibil') in primary and secondary, organic or functional affections of the gall bladder and biliary system.] Zeitschrift fur Allgemeinmedizin 1975, 51(5): 237-241.

Kopp H. Choleretsche Wirkung und Vertraeglichkeit von Chol-Kugeletten® bei Cholezystopathien. Therapiewoche 1979, 29: 5645-5655.

Lagrange E, Aurousseau M. Effect of spray-dried product of Fumaria officinalis on experimental gall bladder lithiasis in mice. Ann Pharm Fr 1973, 31: 357-362. Abstract only.

Madaus G. Lehrbuch der biogischen Heilmittel Band II, 1979, 1391-1397.

Mardirossian ZH, et al. Alkaloids of Fumaria officinalis. Phytochemistry 1983, 22: 759-761.

Martindale. The Extra Pharmacopoeia. 31^st ed. RPS, London 1996.

Massa V, et al. Sur les pigments phenoliques du Fumaria officinalis L. Trav Soc Pharm Montpellier 1971, 31: 233-236. Abstract only.

Murav'eva DA, et al. Isolation of fumaritine from Fumaria officinalis. Khim Farm Zh 1974, 8: 32-34. Abstract only.

Müscher CH. Fumarinhaltiges Amphocholeretikum Cholezystopathien und Hepatopathien. Ärztliche Praxis 1971, 49: 2655-2656.

Paris RR, Moyse H. Précis de Matière Médicale Tome II, Masson, Paris 1981, 207-208.

PDR for Herbal Medicines. Gruenwald J, Brendler T, Jaenicke C, LaGow B, editors. 4th ed. Thomson PDR, Montvale 2007, 340.

Pharmacopée Française Codex medicamentarius Gallicus. Fumeterre. Masson et Cie, Paris 1908, 308.

Preininger V. The pharmacology and toxicology of the papaveraceae alkaloids. In: RHF Manske, ed.

The Alkaloids XV. Academic Press, London 1975, 207-261.

Reynier M, Lagrange E, Godard F. Action du nebulisat de Fumeterre officinal sur la musculature lisse. [Fumaria officinalis spray action on smooth muscles.] Travaux de la Société de Pharmacie de Montpellier 1977, 37(2): 85-102. Abstract only.

Reynier M, Lagrange E, Haring J, Vigouroux M. Effet du nebulisat de Fumeterre, de la Protopine et de la Papaverine sur la secretion biliaire du rat en hypocholerese. [Fumaria spray, protopine and papaverine effects on hypocholeresis rat biliary secretion.] Travaux de la Societe de Pharmacie de Montpellier 1977, 37(2): 73-84. Abstract only.

Roux M. Le nebulisat de fumeterre dans la régulation des troubles de intestinaux chroniques d'origine biliaire. Gazette Médicale de France 1977, 84(34): 3794-3798.

Salembier Y. Study of the action of the aerosol Fumeterre on choleresis in 33 patients with external biliary drainage. Lille Méd 1967, 12(9): 1134-1137. Abstract only.

The Review of Natural Products. 4^th ed. Lippincott Williams & Wilkins, Wolters Kluwer Health Inc. 2005, 458-460.

Torck M, et al. Flavonoids of Fumaria officinalis L. Ann Pharm Fr 1971, 29: 591-596. Abstract only.

Van Hellemont J. Compendium de Phytothérapie. Association Pharmaceutique Belge, 1986, 169-171.

Wawrzynowicz T, Waksmundzki A, Soczewinski E. Partition chromatography and countercurrent distribution of alcaloids of Fumaria officinalis - I. Chromatographic separation of ternary bases. Chromatographia 1968, 1(7-8): 327-331.

Wichtl M. Teedrogen und Phytopharmaka. 4^th ed. WVG, Stuttgart 1998.

Wynne PM, Vine JH, Amiet RG. Protopine alkaloids in horse urine. J Chromatography B: Anal Techn Biomed Life Sc 2004, 811: 85-91.

Zacharewicz M, Chorazy W, Mossor ST, Zacharewicz M Jr. Fumaria Nebulisat in der Bechandlung von Gallenwegerkrankungen. Wienner Medizinische Wochenschrift 1979, 8: 222-224.

Zawodsky, L. Klinische erfahrungen mit dem amphocholeretikum oddibil. [Clinical experience with Fumaria officinalis nebulisate, an amphocholinergic agent.] Wiener Medizinische Wochenschrift 1974, 124(46): 677-680.

List of references supporting the assessment of Fumaria officinalis L., herba

EMA/HMPC/576233/2010

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