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Antiseptic Gargle And Mouthwash

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Document: spc-doc_PL 41318-0034 change

SUMMARY OF PRODUCT CHARACTERISTICS

1 NAME OF THE MEDICINAL PRODUCT

Antiseptic Gargle and Mouthwash

2 QUALITATIVE AND QUANTITATIVE COMPOSITION

Phenol BP 0.7 1% w/v

3 PHARMACEUTICAL FORM

Mouthwash

4 CLINICAL PARTICULARS

4.1 Therapeutic indications

Used to freshen breath and soothing sore throats. Use as a mouthwash

4.2 Posology and method of administration

Dilute one part of the solution with three parts of warm water. Thoroughly rinse the mouth or gargle with the diluted product for up to 20 seconds morning and evening or more frequently if required.

4.3 Contraindications

Hypersensitivity to the active or any of the excipients (6.1).

The label states:

-Do not swallow

-Any unused diluted products should be discarded

4.5 Interaction with other medicinal products and other forms of interaction

No interaction studies have been performed.

4.6 Pregnancy and lactation

Acceptable for use during pregnancy and lactation.

4.7 Effects on ability to drive and use machines

No studies on the effect on the ability to drive and use machines have been performed.

4.8 Undesirable effects

None stated.

4.9 Overdose

When taken by mouth in large doses, Phenol causes extensive local corrosion with pain, nausea, vomiting, sweating and diarrhoea. Treatment is by emptying the stomach by aspiration and lavage, taking care to avoid perforation. Keep the patient warm and treat pulmonary oedema, systemic acidosis, respiratory failure, and circulatory failure symptomatically. Respiration may have to be assisted.

5 PHARMACOLOGICAL PROPERTIES

5.1    Pharmacodynamic properties

Phenol in the solution acts as a bacteriostatic thus removing infection.

5.2    Pharmacokinetic properties

Phenol is absorbed by the mucous membranes and is metabolised to phenyl glucuronide and phenyl sulphate, and small amounts are oxidised to catechol and quinol which are mainly conjugated. The metabolites are excreted in the urine; on oxidation to quinones. They may tint the urine green.

5.3    Preclinical safety data

None stated.

6 PHARMACEUTICAL PARTICULARS

6.1 List of excipients

Glycerine Peppermint Oil Amaranth Solution Water


BP

BP

BP

to


12.5% v/v 0.08% v/v 1.4% v/v 100% v/v


6.2 Incompatibilities

None known.

6.3 Shelf life

3 Years

None stated.


6.5


Nature and contents of container


White flint glass Winchester with a plastic cap 200ml Plastic container with plastic cap 2000ml

White flint glass Winchester with a plastic cap 200ml (available in a cardboard carton which also contains a measuring cup),


6.6


Special precautions for disposal

None stated.


7


MARKETING AUTHORISATION HOLDER

GlobeGen Laboratories Ltd,

1406 Coventry Road,

South Yardley,

Birmingham,

B25 8AE United Kingdom


8


MARKETING AUTHORISATION NUMBER(S)

PL 41318/0034


DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION


14/01/2009


10 DATE OF REVISION OF THE TEXT

25/10/2016