e-Voke 15 mg

Electronic Inhaler

(Nicotine 15 mg per cartridge)

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

•    Always use this medicine exactly as described in this leaflet or as your doctor, pharmacist or nurse has told you.

•    Keep this leaflet. You may need to read it again.

•    Askyour pharmacist if you need more information or advice.

If you get any side effects, talkto your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

What is in this leaflet

1.    What e-Voke is and what it is used for

2.    What you need to know before you use e-Voke

3.    Howto use e-Voke

4.    Possible side effects

5.    Howto store e-Voke

6.    Contents of the pack and other information

1. What e-Voke is and what it is used for

e-Voke contains nicotine. It belongs to a group of medicines known as nicotine replacement therapy (NRT).

e-Voke is used to relieve and /or prevent withdrawal symptoms and reduce the cravings you get when you try to stop smoking or when you cut down the number of cigarettes you smoke. e-Voke Inhalation Cartridges (called cartridges) are for use only with e-Voke Electronic Inhaler (called inhaler).

Ideally you should always aim to stop smoking. You can use e-Voke to achieve this by using it to completely replace all your cigarettes.

You can also use e-Voke to help you to cut down the number of cigarettes you smoke if you feel unable to stop smoking completely, or you only want to replace some cigarettes.

e-Voke may also help increase your motivation to quit smoking. To help you quit smoking you should also try to use a behavioural support programme to increase your chances of success.

How does e-Voke work?

When you stop smoking or cut down the number of cigarettes you smoke, your body misses the nicotine that you have been getting from cigarettes. You may experience unpleasant feelings and a strong desire to smoke (craving). The nicotine you get from using e-Voke replaces the nicotine you were getting from cigarettes. This relieves the unpleasant withdrawal symptoms. It will also help to stop your craving to smoke.

Benefits you can get from using NRT instead of smoking

You may think that smoking helps relieve feelings of anxiety and stress, but it does not deal with the cause of stress and leads to a number of serious diseases. In addition, the feeling of relaxation after smoking is temporary, with withdrawal symptoms and cravings soon returning.

Nicotine replacement therapy, such as e-Voke, can help relieve nicotine withdrawal symptoms such as irritability, low mood, anxiety, restlessness and cravings when used in place of cigarettes. NRT may benefit smokers who want to quit, by helping to control weight gain that may be experienced when trying to stop smoking.

It is the toxins in cigarette smoke such as tar, lead, cyanide and ammonia that cause smoking related disease and death, not the nicotine. The benefits of stopping smoking clearly outweigh any potential risk from using nicotine from NRT.

2. What you need to know before you use e-Voke

This medicine can be used by adults only.

Do not use e-Voke:

•    if you are allergic to nicotine or any of the other ingredients of this medicine (listed in section 6).

•    ifyou are under 18 years of age.

Warnings and precautions

Talkto your doctor, pharmacist or nurse before using e-Voke if any of the following apply to

you:

•    ifyou are in hospital because of heart disease (including heart attack, stroke and problems with your heart rate or rhythm). Ifyou have another heart condition but are not in hospital, using NRT is better than continuing to smoke.

•    ifyou have a stomach ulcer, duodenal ulcer, irritation or inflammation of the stomach or throat.

•    ifyou have liver or kidney problems.

•    ifyou have a long term throat disease or difficulty breathing due to bronchitis, emphysema or asthma. e-Voke may not be suitable for you to use and you may be advised to use a different type of NRT.

e-Voke PIL15 mg v2,02-10-15

Talkto your doctor, pharmacist or nurse before using e-Voke if any of the following apply to you:

•    ifyou have an overactive thyroid gland or have a phaeochromocytoma (a tumour of the adrenal gland that can affect blood pressure).

•    ifyou have diabetes - you will need to monitor your blood sugar levels more often when starting to use e-Voke as nicotine may affect these levels. Askyour doctor or pharmacist about this.

•    Ifyou are pregnant or breast feeding - you may be able to use nicotine replacement therapy (NRT) to help you give up smoking but you should try to give up without it. See 'Pregnancy and breast-feeding'.

•    Ifyou are taking any other medicines prescribed by your doctor on a regular basis

(See 'Other Medicines and e-Voke').

Pregnancy and breast-feeding Ifyou are pregnant:

You should try to give up smoking without NRT. Stopping completely is by far the best option. The earlier and quicker you do this the better it is for you and your baby.

Ifyou can't give up smoking, you can use NRT as a safer alternative to smoking for you and your baby. However you should talkto your doctor, nurse or pharmacist for more advice. Nicotine replacement therapies that are used intermittently may be preferable to nicotine patches. However, patches may be more suitable ifyou have nausea or sickness.

Ifyou are breast-feeding:

You should try to give up smoking without NRT.

Ifyou can't give up smoking you should use NRT products that are taken intermittently (not patches), however you should talkto your doctor, nurse or pharmacist for advice.

Breast-feed your baby just before you use NRT to make sure your baby gets the smallest amount of nicotine possible.

The amount of nicotine that the baby may receive ifyou use NRT is considerably smaller and less harmful than the second-hand smoke they would inhale ifyou smoked.

Other medicines and e-Voke

Tell your doctor or pharmacist ifyou are taking any other medicines, particularly:

•    theophylline (used to treat breathing problems)

•    clozapine (used to treat schizophrenia)

•    ropinirole (used to treat restless legs)

Stopping smoking or cutting down slows your metabolism. Your doctor may need to change the dose of these medicines.

Nicotine products and children

This product contains small cartridges which could cause choking if a child attempts to swallow one. Nicotine can be very dangerous to children and can sometimes be fatal.

If a child accidentally uses, sucks, swallows or chews an e-Voke Inhalation Cartridge take them to your nearest Accident and Emergency department immediately. Take the medicine and this leaflet with you. Nicotine ingestion by a child may cause severe poisoning.

Always keep e-Voke out of reach and sight of children and dispose of carefully (see section 5).

3. How to use e-Voke

Always use this medicine exactly as described in this leaflet. Talk with your doctor, pharmacist or nurse ifyou are not sure.

e-Voke is made up of: e-Voke Electronic Inhaler (inhaler) and Inhalation Cartridges (cartridges).

•    Do not use the cartridges with any other electronic inhaler. There is a risk of serious injury if the cartridges are used in other delivery devices.

Adults aged 18 years and over:

•    10 inhalations is typically the amount you need before your cravings will go away.

•    10 inhalations contain approximately 0.56mg of nicotine, although the actual amount will vary depending on how deeply you inhale. How often you need to use the inhaler depends on how many cigarettes you used to smoke.

•    130 inhalations is about the amount in each cartridge. This depends on the depth and length of your inhalations.

•    5 cartridges per day is the maximum you should use. It is up to you how many inhalations you use and how often you use them.

Ifyou are able to stop smoking you should use e-Voke, when needed, in place of cigarettes. As soon as you can, you should reduce the number of cartridges you use until you have stopped using them completely. You should continue using e-Voke until cravings for nicotine disappear.

Ifyou have quit smoking and want to stop using e-Voke but are finding this difficult you should contact your doctor, pharmacist or nurse for advice. Follow the instructions below to make sure you use your inhaler correctly.

The amount of nicotine that you get from e-Voke is not affected by the surrounding temperature.

Ifyou use more e-Voke than you should

Ifyou have used more than the recommended number of cartridges, you may experience nausea (feeling sick), salivation, pain in your abdomen, diarrhoea, sweating, headache, dizziness, hearing disturbance or weakness.

Ifyou get any of these effects, contact a doctor or your nearest hospital Accident and Emergency department immediately. Take this leaflet and the pack with you.

Ifyou have any further questions on the use of this medicine, askyour doctor, pharmacist or nurse.

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