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Merocets

Document: spc-doc_PL 04425-0692 change

SUMMARY OF PRODUCT CHARACTERISTICS

1    NAME OF THE MEDICINAL PRODUCT

Merocets

2    QUALITATIVE AND QUANTITATIVE    COMPOSITION

Cetylpyridinium chloride 1.4mg/lozenge.

Also contains sucrose, glucose liquid and sunset yellow. For the full list of excipients, see section 6.1.

3    PHARMACEUTICAL FORM

Lozenge

4    CLINICAL PARTICULARS

4.1    Therapeutic indications

Relief of sore throat and other symptoms associated with mouth and throat infections.

4.2    Posology and method of administration

Oral (lozenge).

Adults, the elderly and children 6 years and over: One lozenge every 3 hours. Allow the lozenge to dissolve slowly in the mouth.

Children under 6 years: not recommended.

4.3 Contraindications

Hypersensitivity to the active substance or to any of the excipients

4.4 Special warnings and precautions for use

Label: If sore throat persists for more than three days consult your doctor. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

Sunset yellow (E110) may cause allergic reactions Keep out of the reach and sight of children.

4.5 Interaction with other medicinal products and other forms of interaction

None stated.

4.6 Fertility, Pregnancy and lactation

There is no or inadequate evidence of safety of cetylpyridinium chloride in human pregnancy but it has been in wide use for many years without apparent ill-consequences. No data are available on the use of Merocets lozenges in pregnancy.

However, as with all medicines, caution should be exercised during pregnancy and lactation.

4.7 Effects on ability to drive and use machines

Not applicable.

4.8 Undesirable effects

Very rare reports of urticaria. Infrequent and transient complaints of a burning sensation of the mouth.

4.9 Overdose

No experience of overdosage but normal procedures of gastric lavage and maintenance of respiration and circulation (using vasopressor drugs if necessary) should apply.

5.1    Pharmacodynamic properties

Cetylpyridinium chloride is a surface active quartemary ammonium compound with antibacterial properties.

5.2    Pharmacokinetic properties

Cetylpyridinium chloride exerts its antimicrobial activity topically in the mouth and throat as it dissolves from the lozenge. Pharmacokinetic data are not available.

5.3    Preclinical safety data

None stated.

6    PHARMACEUTICAL PARTICULARS

6.1    List of excipients

Sucrose, glucose liquid, peppermint oil, sunset yellow (E110), quinoline yellow (E104), ethyl alcohol, purified water.

6.2    Incompatibilities

Not applicable.

6.3    Shelf life

60 months unopened.

6.4    Special precautions for storage

Do not store above 25°C

6.5


Nature and contents of container


PVC/PVdC/aluminium foil laminate blister in cardboard cartons. Packs of 24, sample pack of 8 lozenges.


6.6


Special precautions for disposal

None stated.


7


MARKETING AUTHORISATION HOLDER

Aventis Pharma Limited

One Onslow Street

Guildford

Surrey

GU1 4YS

UK

or trading as


Sanofi-aventis or Sanofi One Onslow Street Guildford Surrey


GU1 4YS UK


8


MARKETING AUTHORISATION NUMBER(S)

PL 04425/0692

DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION


31/01/2006


10 DATE OF REVISION OF THE TEXT

17/12/2014