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Nutraplus Cream

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SUMMARY OF PRODUCT CHARACTERISTICS

1    NAME OF THE MEDICINAL PRODUCT

Nutraplus 10% w/w Cream

2    QUALITATIVE AND QUANTITATIVE    COMPOSITION

Each gram of cream contains 100mg of Urea

Excipients with known effect:    Methyl parahydroxybenzoate (E218) 1.8 mg/g, Propyl

parahydroxybenzoate (E216) 0.9 mg/g, Propylene glycol 45mg/g,

Cetearyl alcohol 18.0 mg/g - 22.5 mg/g For the full list of excipients see section 6.1

3.    PHARMACEUTICAL FORM

Cream

Smooth white, almost odourless cream (water in oil emulsion).

4    CLINICAL PARTICULARS

4.1    Therapeutic indications

An emollient, moisturising and protective cream for the treatment of dry or damaged skin.

4.2    Posology and method of administration

Adults, paediatric population and older people

Apply evenly to the dry skin areas two to three times daily, or as directed by the physician or pharmacist.

4.3    Contraindications

Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.

Special warnings and precautions for use

4.4


Avoid contact with the eyes. If irritation occurs, discontinue use temporarily.

4.5    Interaction with other medicinal products and other forms of interaction

None known

4.6    Fertility, pregnancy and lactation

No known effects. Use at the discretion of the physician or pharmacist.

4.7    Effects on ability to drive and use machines

Nutraplus has no influence on the ability to drive and use machines.

4.8    Undesirable effects

None known.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard

4.9    Overdose

Not applicable.

5    PHARMACOLOGICAL PROPERTIES

5.1    Pharmacodynamic properties

Pharmacotherapeutic group:Protectives and emollients.

ATC code: D02 AE01

Urea is a recognised hydrating agent that has been widely used topically to treat dry or damaged skin.

5.2    Pharmacokinetic properties

Not applicable. Nutraplus is a topical (cutaneous) preparation.

5.3


Preclinical safety data

No specific information is presented given the widespread use of topically applied urea on humans over many years.

6 PHARMACEUTICAL PARTICULARS

6.1    List of excipients

Glycerol monostearate Octyl palmitate Myristyl lactate Mineral oil

Promulgen D (contains Cetearyl alcohol and ceteareth-20)

Propylene glycol

Propyl parahydroxybenzoate (E216)

Methyl parahydroxybenzoate (E218)

Purified water

6.2    Incompatibilities

Not applicable.

6.3    Shelf life

3 years.

6.4    Special precautions for storage

Do not store above 25oC.

As with all medicines, Nutraplus Cream should be stored out of the sight and reach of children.

6.5    Nature and contents of container

White, polyethylene tube with a white polypropylene screw cap as the closure.

Pack sizes: 60g and 100g

Not all pack sizes may be marketed.

6.6    Special precautions for disposal

No special requirements.

Any unused medicinal product or waste material should be disposed of in accordance with local requirements.

7.    MARKETING AUTHORISATION HOLDER

Galderma (UK) Limited,

Meridien House 69-71 Clarendon Road

Watford

Herts

WD17 IDS UK

8. MARKETING AUTHORISATION NUMBER

PL 10590/0002

9. DATE OF FIRST AUTHORISATION/RENEWAL OF AUTHORISATION

4 June 1991

10 DATE OF REVISION OF THE TEXT

03/10/2013