Salmeterol 25micrograms Evohaler
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25micrograms
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at:www.mhra.gov.uk/yellowcard. By reporting side effects, you can help provide more information on the safety of this medicine
5. How to store Serevent Evohaler
• Keep out of the sight and reach of children.
• Straight after use, replace the mouthpiece cover firmly and click it into position. Do not use excessive force.
• Do not store above 30°C.
• The metal canister contains a pressurised liquid. Do not pierce or burn it even when it is apparently empty.
• Do not use Serevent Evohaler after the expiry date which is stated on the label and carton. The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
If your medicine becomes discoloured or show any signs of deterioration, you should seek the advice of your pharmacist.
6. Contents of the pack and other information
What Serevent Evohaler contains
• Each puff provides 25micrograms of the active ingredient salmeterol (as xinafoate).
• There are 120 puffs in each canister.
• The other ingredient is norflurane (HFA 134a).
What Serevent Evohaler looks like and contents of the pack
A pressurised metered dose aerosol inhaler, comprising a green plastic body with a light green removable dust cap. The pressurised aluminum canister contains a white to off white inhalation suspension.
Manufactured by: Laboratories Vitoria, S.A., Rua Elias Garcia, 28, Venda Nova, 2700-327 Amadora, Portugal
Procured from within the EU and repackaged by the Product Licence holder:
B&S Healthcare, Unit 4, Bradfield Road, Ruislip, Middlesex, HA4 0NU.
SEREVENT™ 25 micrograms EVOHALER™ PL No: 18799/1953
Leaflet date: 04.11.2014
Evohaler, Serevent Evohaler, Haleraid and Volumatic are trademarks of the GlaxoSmithKline group of companies
Package Leaflet: Information for the User
Serevent™
Evohaler™
Pressurised inhalation, suspension
(salmeterol xinafoate)
Read all of this leaflet carefully before you start taking this medicine.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
The name of your medicine is Serevent 25micrograms Evohaler but will be referred to as Serevent Evohaler or Serevent throughout this leaflet.
In this leaflet:
1 What Serevent Evohaler is and what it is used for
2 What you need to know before you use Serevent Evohaler
3 How to use Serevent Evohaler
4 Possible side effects
5 How to store Serevent Evohaler
6 Contents of the pack and other information
1. What Serevent Evohaler is and what it is used for
• Serevent Evohaler contains the medicine salmeterol. It is a 'long-acting bronchodilator'. It helps the airways in the lungs to stay open. This makes it easier for air to get in and out. The effects are usually felt within 10 to 20 minutes and last for 12 hours or more.
• The doctor has prescribed it to help prevent breathing problems. These could be caused by asthma. Taking Serevent Evohaler regularly will help prevent asthma attacks. This also includes asthma brought on by exercise or at night.
• Taking Serevent Evohaler regularly will also help prevent breathing problems caused by other chest illnesses such as Chronic Obstructive Pulmonary Disease (COPD).
• Serevent Evohaler helps to stop breathlessness and wheezing coming on. It does not work once you are breathless or wheezy. If that happens you need to use a fast acting 'reliever' medicine, such as salbutamol.
• Serevent Evohaler is supplied to you in an inhaler. You breathe the medicine directly into your lungs.
• Serevent Evohaler contains norflurane. This is less harmful to the environment than older inhalers. Older inhalers may taste differently to Serevent Evohaler. This will make no difference to how your medicine works.
If you are being treated for asthma, you should always be given both a Serevent
and a steroid inhaler to use together.
2. What you need to know before you use Serevent Evohaler
Do not take Serevent Evohaler if:
you are allergic (hypersensitive) to salmeterol or to the other ingredient norflurane (HFA 134a)
Take special care with Serevent Evohaler
• If your asthma or breathing gets worse tell your doctor straight away. You may
find that you feel more wheezy, your chest feels tight more often or you may need to use more of your fast acting 'reliever' medicine. If any of these happen, do not increase your number of puffs of Serevent. Your chest condition may be getting worse and you could become seriously ill. See your doctor as you may need a change in asthma treatment.
• Once your asthma is well controlled your doctor may consider it appropriate to gradually reduce the dose of Serevent.
• If you have been prescribed Serevent for your asthma, continue to use any other asthma medication you are already taking. These could include a steroid inhaler or steroid tablets. Continue taking the same doses as before, unless your doctor tells you otherwise. Do this even if you feel much better. Do not stop taking your steroid inhaler (or any steroid tablets) when you start using Serevent.
• Your doctor may want to check your health regularly if you have an overactive thyroid gland, diabetes mellitus (Serevent may increase your blood sugar) or heart disease, including an irregular or fast heartbeat.
Other medicines and Serevent
• Tell your doctor if you are taking or have recently taken any other medicines. This includes those for asthma or any other medicines obtained without a prescription. This is because Serevent may not be suitable to be taken with other medicines.
• Inform your doctor before using Serevent if you are currently being treated for any fungal infections with medicines containing ketoconazole or itraconazole, or if you are being treated for HIV with ritonavir. These medicines may increase the risk of you experiencing side effects with Serevent, including irregular heart beats, or may make side effects worse.
• Beta-blockers should be avoided when taking Serevent, unless your doctor tells you to take them. Beta-blockers, including atenolol, propranolol and sotalol, are mostly used for high blood pressure or other heart conditions. Please tell your doctor if you are taking beta-blockers or have recently been prescribed beta-blockers as they may reduce or abolish the effects of salmeterol.
• Serevent can reduce the amount of potassium in your blood. If this happens you may notice an uneven heartbeat, muscle weakness or cramp. This is more likely to happen if you take Serevent with some medicines used to treat high blood pressure (diuretics) and other medicines used to treat breathing problems such as theophylline or steroids. Your doctor may ask for you to have blood tests to check the amount of potassium in your blood. If you have any concerns discuss them with your doctor.
Pregnancy and breast-feeding
If you are pregnant or breast feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Driving and using machines
The possible side effects associated with Serevent Evohaler are unlikely to affect your ability to drive or use machines.
3. How to use Serevent Evohaler
8 Wait about half a minute between taking each puff of medicine and then repeat steps 3 to 7.
9 After use always replace the mouthpiece cover immediately to keep out dust. Replace the cover by firmly pushing and snapping the cap into position.
Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
• If you are being treated for asthma, you should always be given both a Serevent Evohaler and a steroid inhaler to use together.
• Use Serevent Evohaler every day, until your doctor advises you to stop.
• You will start to feel your medicine working within the first day of use.
Serevent Evohaler is for inhalation by mouth only.
Adults and adolescents aged 12 years and older with Asthma
• The usual starting dose is 2 puffs twice a day.
• For people with more severe asthma, your doctor may increase your dose to 4 puffs twice a day.
Children with Asthma
• In children aged 4 to 12 the usual dose is 2 puffs twice a day.
• Serevent Evohaler is not recommended for use in children below 4 years of age.
Adults with Chronic Obstructive Pulmonary Disease (COPD) including bronchitis and emphysema
• The usual starting dose is 2 puffs twice a day.
• Not applicable for children and adolescents.
Instructions for use
Your doctor, nurse or pharmacist should show you how to use your inhaler. They should check how you use it from time to time. Not using the inhaler properly or as prescribed, may mean that the medicine will not help your asthma or COPD as it should.
The medicine is contained in a pressurised canister in a plastic casing with a mouthpiece.
^ Hold your breath, take the * inhaler from your mouth and your finger from the top of the inhaler. Continue holding your breath for a few seconds, or as long as is comfortable.
Practice in front of a mirror for the first few times. If you see a 'mist' coming from the top of your inhaler or the sides of your mouth you should start again
If you or your child finds it difficult to use Serevent Evohaler, it may be used with other devices to make its use easier e.g. a HaleraidTM or VolumaticTM spacer device. Serevent is also available in an alternative device. Talk to your doctor, nurse or pharmacist for further advice.
Testing your inhaler
. When using your inhaler for
\ time, test that it is working. Remove the mouthpiece cover by gently squeezing the sides with your thumb and forefinger and pull apart.
O To make sure that it works, shake “ it well, point the mouthpiece away from you and press the canister to release two puffs into the air. If you have not used the inhaler for a week or more, also release two puffs of medicine into the air.
Cleaning your inhaler
To stop your inhaler blocking up, it is important to clean it at least once a week.
To clean your inhaler
• Remove the mouthpiece cover.
• Do not remove the metal canister from the plastic casing at any time.
• Wipe the inside and outside of the mouthpiece and the plastic casing with a dry cloth or tissue.
• Replace the mouthpiece cover.
Do not put the metal canister in water.
If you use more Serevent Evohaler than you should
It is important to use the inhaler as instructed. If you accidentally take a larger dose than recommended, talk to your doctor or pharmacist. You may notice your heart beating faster than usual and that you feel shaky and/ or dizzy. You may also have a headache, muscle weakness and aching joints.
If you forget to use Serevent Evohaler
Do not take a double dose to make up for a missed dose. Just take your next dose at the usual time.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Using your inhaler
It is important to start to breathe in as slowly as possible just before using your inhaler.
^ Stand or sit upright when using your inhaler.
O Remove the mouthpiece cover (as shown in the first picture).Check inside and “ outside to make sure that the mouthpiece is clean and free of objects.
3 Shake the inhaler 4 or 5 times to ensure that any loose objects are removed and that the contents of the inhaler are evenly mixed
Hold the inhaler upright with your thumb 4 on the base, below the mouthpiece. Breath' out as far as is comfortable.
5 Place the mouthpiece in your mouth between your teeth. Close your lips around it. Do not bite.
6 Breathe in through your mouth. Just after starting to breathe in, press down on the top of the canister to release a puff of medicine. Do this while still breathing in steadily and deeply.
Like all medicines, Serevent can cause side effects, although not everybody gets them. To reduce the chances of side effects, your doctor will prescribe the lowest dose of Serevent to control your asthma or COPD. These are the side effects reported by people taking Serevent.
Allergic reactions: you may notice your breathing suddenly gets worse after using Serevent. You may be very wheezy and cough. You may also notice itching and swelling (usually of the face, lips, tongue or throat). If you get these effects or they happen suddenly after using Serevent, tell your doctor straight away. Allergic reactions to Serevent are very rare (they affect less than 1 person in 10,000).
Other side effects are listed below:
Common (affects less than 1 person in 10):
• Muscle cramps
• Feeling shaky; fast or uneven heartbeat (palpitations), headache, shaking hands (tremor). Tremors are more likely if you are taking more than two puffs twice daily. These side effects do not last long and happen less as treatment with Serevent continues.
Uncommon (affects less than 1 person in 100):
• Rash
• Very fast heart rate (tachycardia). This is more likely to happen if you are taking more than two puffs twice daily.
• Feeling nervous.
Rare (affects less than 1 person in 1,000):
• Feeling dizzy
• Being unable to sleep or finding sleep difficult
• A reduction in the amount of potassium in your blood (you may get an uneven heartbeat, muscle weakness, cramp).
Very rare (affects less than 1 person in 10,000):
• Breathing difficulties or wheezing that gets worse straight after taking Serevent.
If this happens stop using your Serevent Evohaler. Use your fast-acting 'reliever' inhaler to help your breathing and tell your doctor straight away.
• Uneven heartbeat or your heart gives an extra beat (arrhythmias). If this happens do not stop using Serevent but tell your doctor.
• Increases in the amount of sugar (glucose) in your blood (hyperglycaemia). If you have diabetes, more frequent blood sugar monitoring and possibly adjustment of your usual diabetic treatment may be required.
• Sore mouth or throat
• Feeling sick (nausea)
• Aching, swollen joints or chest pain
POM
Package Leaflet: Information for the User
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at:www.mhra.gov.uk/yellowcard. By reporting side effects, you can help provide more information on the safety of this medicine
5. How to store Salmeterol Evohaler
• Keep out of the sight and reach of children.
• Straight after use, replace the mouthpiece cover firmly and click it into position. Do not use excessive force.
• Do not store above 30°C.
• The metal canister contains a pressurised liquid. Do not pierce or burn it even when it is apparently empty.
• Do not use Salmeterol Evohaler after the expiry date which is stated on the label and carton. The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
If your medicine becomes discoloured or show any signs of deterioration, you should seek the advice of your pharmacist.
6. Contents of the pack and other information
What Salmeterol Evohaler contains
• Each puff provides 25micrograms of the active ingredient salmeterol (as xinafoate).
• There are 120 puffs in each canister.
• The other ingredient is norflurane (HFA 134a).
What Salmeterol Evohaler looks like and contents of the pack
A pressurised metered dose aerosol inhaler, comprising a green plastic body with a light green removable dust cap. The pressurised aluminum canister contains a white to off white inhalation suspension.
Manufactured by: Laboratories Vitoria, S.A., Rua Elias Garcia, 28, Venda Nova, 2700-327 Amadora, Portugal
Procured from within the EU and repackaged by the Product Licence holder:
B&S Healthcare, Unit 4, Bradfield Road, Ruislip, Middlesex, HA4 0NU.
SALMETEROL 25 micrograms EVOHALER PL No: 18799/1953
Leaflet date: 04.11.2014
Salmeterol 25micrograms
Evohaler
Pressurised inhalation, suspension
(salmeterol xinafoate)
Read all of this leaflet carefully before you start taking this medicine.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
The name of your medicine is Salmeterol 25micrograms Evohaler but will be referred to as Salmeterol Evohaler or Salmeterol throughout this leaflet.
In this leaflet:
1 What Salmeterol Evohaler is and what it is used for
2 What you need to know before you use Salmeterol Evohaler
3 How to use Salmeterol Evohaler
4 Possible side effects
5 How to store Salmeterol Evohaler
6 Contents of the pack and other information
1. What Salmeterol Evohaler is and what it is used for
• Salmeterol Evohaler contains the medicine salmeterol. It is a 'long-acting bronchodilator'.
It helps the airways in the lungs to stay open. This makes it easier for air to get in and out. The effects are usually felt within 10 to 20 minutes and last for 12 hours or more.
• The doctor has prescribed it to help prevent breathing problems. These could be caused by asthma. Taking Salmeterol Evohaler regularly will help prevent asthma attacks. This also includes asthma brought on by exercise or at night.
• Taking Salmeterol Evohaler regularly will also help prevent breathing problems caused by other chest illnesses such as Chronic Obstructive Pulmonary Disease (COPD).
• Salmeterol Evohaler helps to stop breathlessness and wheezing coming on. It does not work once you are breathless or wheezy. If that happens you need to use a fast acting 'reliever' medicine, such as salbutamol.
• Salmeterol Evohaler is supplied to you in an inhaler. You breathe the medicine directly into your lungs.
• Salmeterol Evohaler contains norflurane. This is less harmful to the environment than older inhalers. Older inhalers may taste differently to Salmeterol Evohaler. This will make no difference to how your medicine works.
If you are being treated for asthma, you should always be given both a Salmeterol
and a steroid inhaler to use together.
2. What you need to know before you use Salmeterol Evohaler
Do not take Salmeterol Evohaler if:
you are allergic (hypersensitive) to salmeterol or to the other ingredient norflurane (HFA 134a)
Take special care with Salmeterol Evohaler
• If your asthma or breathing gets worse tell your doctor straight away. You may
find that you feel more wheezy, your chest feels tight more often or you may need to use more of your fast acting 'reliever' medicine. If any of these happen, do not increase your number of puffs of Salmeterol. Your chest condition may be getting worse and you could become seriously ill. See your doctor as you may need a change in asthma treatment.
• Once your asthma is well controlled your doctor may consider it appropriate to gradually reduce the dose of Salmeterol.
• If you have been prescribed Salmeterol for your asthma, continue to use any other asthma medication you are already taking. These could include a steroid inhaler or steroid tablets. Continue taking the same doses as before, unless your doctor tells you otherwise. Do this even if you feel much better. Do not stop taking your steroid inhaler (or any steroid tablets) when you start using Salmeterol.
• Your doctor may want to check your health regularly if you have an overactive thyroid gland, diabetes mellitus (Salmeterol may increase your blood sugar) or heart disease, including an irregular or fast heartbeat.
Other medicines and Serevent
• Tell your doctor if you are taking or have recently taken any other medicines. This includes those for asthma or any other medicines obtained without a prescription. This is because Salmeterol may not be suitable to be taken with other medicines.
• Inform your doctor before using Salmeterol if you are currently being treated for any fungal infections with medicines containing ketoconazole or itraconazole, or if you are being treated for HIV with ritonavir. These medicines may increase the risk of you experiencing side effects with Salmeterol, including irregular heart beats, or may make side effects worse.
• Beta-blockers should be avoided when taking Salmeterol, unless your doctor tells you to take them. Beta-blockers, including atenolol, propranolol and sotalol, are mostly used for high blood pressure or other heart conditions. Please tell your doctor if you are taking beta-blockers or have recently been prescribed beta-blockers as they may reduce or abolish the effects of salmeterol.
• Salmeterol can reduce the amount of potassium in your blood. If this happens you may notice an uneven heartbeat, muscle weakness or cramp. This is more likely to happen if you take Salmeterol with some medicines used to treat high blood pressure (diuretics) and other medicines used to treat breathing problems such as theophylline or steroids.
Your doctor may ask for you to have blood tests to check the amount of potassium in your blood. If you have any concerns discuss them with your doctor.
Pregnancy and breast-feeding
If you are pregnant or breast feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Driving and using machines
The possible side effects associated with Salmeterol Evohaler are unlikely to affect your ability to drive or use machines.
3. How to use Salmeterol Evohaler
8 Wait about half a minute between taking each puff of medicine and then repeat steps 3 to 7.
9 After use always replace the mouthpiece cover immediately to keep out dust. Replace the cover by firmly pushing and snapping the cap into position.
Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
• If you are being treated for asthma, you should always be given both a Salmeterol Evohaler and a steroid inhaler to use together.
• Use Salmeterol Evohaler every day, until your doctor advises you to stop.
• You will start to feel your medicine working within the first day of use.
Salmeterol Evohaler is for inhalation by mouth only.
Adults and adolescents aged 12 years and older with Asthma
• The usual starting dose is 2 puffs twice a day.
• For people with more severe asthma, your doctor may increase your dose to 4 puffs twice a day.
Children with Asthma
• In children aged 4 to 12 the usual dose is 2 puffs twice a day.
• Salmeterol Evohaler is not recommended for use in children below 4 years of age.
Adults with Chronic Obstructive Pulmonary Disease (COPD) including bronchitis and emphysema
• The usual starting dose is 2 puffs twice a day.
• Not applicable for children and adolescents.
Instructions for use
Your doctor, nurse or pharmacist should show you how to use your inhaler. They should check how you use it from time to time. Not using the inhaler properly or as prescribed, may mean that the medicine will not help your asthma or COPD as it should.
The medicine is contained in a pressurised canister in a plastic casing with a mouthpiece.
^ Hold your breath, take the * inhaler from your mouth and your finger from the top of the inhaler. Continue holding your breath for a few seconds, or as long as is comfortable.
Practice in front of a mirror for the first few times. If you see a 'mist' coming from the top of your inhaler or the sides of your mouth you should start again
If you or your child finds it difficult to use Salmeterol Evohaler, it may be used with other devices to make its use easier e.g. a HaleraidTM or VolumaticTM spacer device. Salmeterol is also available in an alternative device. Talk to your doctor, nurse or pharmacist for further advice.
Testing your inhaler
. When using your inhaler for
\ time, test that it is working. Remove the mouthpiece cover by gently squeezing the sides with your thumb and forefinger and pull apart.
O To make sure that it works, shake “ it well, point the mouthpiece away from you and press the canister to release two puffs into the air. If you have not used the inhaler for a week or more, also release two puffs of medicine into the air.
Cleaning your inhaler
To stop your inhaler blocking up, it is important to clean it at least once a week.
To clean your inhaler
• Remove the mouthpiece cover.
• Do not remove the metal canister from the plastic casing at any time.
• Wipe the inside and outside of the mouthpiece and the plastic casing with a dry cloth or tissue.
• Replace the mouthpiece cover.
Do not put the metal canister in water.
If you use more Salmeterol Evohaler than you should
It is important to use the inhaler as instructed. If you accidentally take a larger dose than recommended, talk to your doctor or pharmacist. You may notice your heart beating faster than usual and that you feel shaky and/ or dizzy. You may also have a headache, muscle weakness and aching joints.
If you forget to use Salmeterol Evohaler
Do not take a double dose to make up for a missed dose. Just take your next dose at the usual time.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Using your inhaler
It is important to start to breathe in as slowly as possible just before using your inhaler.
^ Stand or sit upright when using your inhaler.
O Remove the mouthpiece cover (as shown in the first picture).Check inside and “ outside to make sure that the mouthpiece is clean and free of objects.
3 Shake the inhaler 4 or 5 times to ensure that any loose objects are removed and that the contents of the inhaler are evenly mixed
Hold the inhaler upright with your thumb 4 on the base, below the mouthpiece. Breath' out as far as is comfortable.
5 Place the mouthpiece in your mouth between your teeth. Close your lips around it. Do not bite.
6 Breathe in through your mouth. Just after starting to breathe in, press down on the top of the canister to release a puff of medicine. Do this while still breathing in steadily and deeply.
Like all medicines, Salmeterol can cause side effects, although not everybody gets them. To reduce the chances of side effects, your doctor will prescribe the lowest dose of Salmeterol to control your asthma or COPD. These are the side effects reported by people taking Salmeterol.
Allergic reactions: you may notice your breathing suddenly gets worse after using Salmeterol. You may be very wheezy and cough. You may also notice itching and swelling (usually of the face, lips, tongue or throat). If you get these effects or they happen suddenly after using Salmeterol, tell your doctor straight away. Allergic reactions to Salmeterol are very rare (they affect less than 1 person in 10,000).
Other side effects are listed below:
Common (affects less than 1 person in 10):
• Muscle cramps
• Feeling shaky; fast or uneven heartbeat (palpitations), headache, shaking hands (tremor). Tremors are more likely if you are taking more than two puffs twice daily. These side effects do not last long and happen less as treatment with Salmeterol continues.
Uncommon (affects less than 1 person in 100):
• Rash
• Very fast heart rate (tachycardia). This is more likely to happen if you are taking more than two puffs twice daily.
• Feeling nervous.
Rare (affects less than 1 person in 1,000):
• Feeling dizzy
• Being unable to sleep or finding sleep difficult
• A reduction in the amount of potassium in your blood (you may get an uneven heartbeat, muscle weakness, cramp).
Very rare (affects less than 1 person in 10,000):
• Breathing difficulties or wheezing that gets worse straight after taking Salmeterol.
If this happens stop using your Salmeterol Evohaler. Use your fast-acting 'reliever' inhaler to help your breathing and tell your doctor straight away.
• Uneven heartbeat or your heart gives an extra beat (arrhythmias). If this happens do not stop using Salmeterol but tell your doctor.
• Increases in the amount of sugar (glucose) in your blood (hyperglycaemia). If you have diabetes, more frequent blood sugar monitoring and possibly adjustment of your usual diabetic treatment may be required.
• Sore mouth or throat
• Feeling sick (nausea)
• Aching, swollen joints or chest pain